Frailty - A measure of your true age
The August edition of Nature Aging has a very interesting review article on frailty. Frailty is a state weakness, most often associated with old age. Indicators of frailty are weakness fatigue weight loss low physical activity poor balance low gait speed visual impairment and cognitive impairment Frailty as a root cause of other age-associated diseases The development of frailty is associated with not just an increased risk of an disability or death from falls but also increased risk of developing physiological diseases including Alzheimer's disease Cardiovascular disease Hypertension and stroke Rheumatoid arthritis and Diabetes Frailty is also linked to an increased susceptibility to infection, including COVID-19. Our skeletal muscles provide an important metabolic stimulus and regulatory function for the rest of our body. The loss of this stimulus and regulation leads is largely responsible for the susceptibility to disease. Adding on to this is a loss of independence wh...